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The U.S. Department of Health and Human Services (HHS) is undergoing a significant transformation in 2025. This comes with the recent news of HHS layoffs in 2025 that slashed 10,000 jobs, reducing the total workforce from 82,000 to 62,000. To say that the impact of HHS job cuts is huge would be an understatement. This HHS restructuring in 2025 has triggered overhaul across critical functions like HR, IT and procurement across its network of agencies, including the FDA, CDC and NIH. For HR professionals, the health department layoffs in 2025 aren’t just another round of federal job cuts. The HHS